Figure_4.tif (2.23 MB)
The rate of transport of different gold nanoparticles.
figure
posted on 2013-12-05, 04:16 authored by Radka Gromnicova, Heather A. Davies, Peddagangannagari Sreekanthreddy, Ignacio A. Romero, Torben Lund, Ivan M. Roitt, James B. Phillips, David K. MaleTEM of (a) 30 nm colloidal gold (Au30), (b) 4 nm glucose-coated nanoparticles (Glu) and (c) 4 nm glutathione-coated nanoparticles (Gln). (d) Rate of transport of the nanoparticles into and across hCMEC/D3 cells 22 hours after application. Values represent mean ± SEM of the number of nanoparticles located beneath the basal plasma membrane or in the cytosol, based on at least 50 TEM images. Data were analysed by Anova (P<0.01 for the basal membrane data), followed by two-tailed t-tests. *P<0.05, ***P<0.001.